Tailored surgery for drug-resistant epilepsy due to temporal pole encephalocele and microdysgenesis
نویسندگان
چکیده
Marco Giulioni *, Laura Licchetta , Francesca Bisulli , Guido Rubboli , Barbara Mostacci , Gianluca Marucci , Matteo Martinoni , Lorenzo Ferri , Lilia Volpi , Fabio Calbucci , Agostino Baruzzi , Paolo Tinuper b,c a IRCCS Istituto delle Scienze Neurologiche di Bologna, Division of Neurosurgery, AUSL di Bologna, Italy b IRCCS Istituto delle Scienze Neurologiche di Bologna, AUSL di Bologna, Italy Department of Biomedical and Neuromotor Sciences, University of Bologna, Italy d IRCCS Istituto delle Scienze Neurologiche di Bologna, Division of Neurology, AUSL di Bologna, Italy Danish Epilepsy Center, Epilepsihospitalet, Dianalund, Denmark f Section of Pathology ‘‘M. Malpighi’’ at Bellaria Hospital, Department of Biomedical and Neuro Motor Sciences, University of Bologna, Bologna, Italy
منابع مشابه
Refractory epilepsy and encephalocele: Lesionectomy or tailored surgery?
We read with great interest the paper entitled ‘‘Tailored surgery for drug-resistant epilepsy due to temporal pole encephalocele and microdysgenesis’’ by Giulioni et al. The authors describe two cases of encephalocele associated with cortical microdysgenesis and assert the necessity to consider an extensive surgical resection in subjects with small encephaloceles, due to the possible concomitan...
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Background: Epilepsy surgery has become a successful treatment option for patients with drug-resistant epilepsies. Objectives: This study aimed to assess temporal lobe epilepsy (TLE) surgery outcome and its association with epilepsy duration, the presence of pre-surgical generalized tonic-clonic seizure (GTCS), and brain MRI findings. Materials & Methods: This retrospective study was perfo...
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The management of medically intractable epilepsy is frequently assisted by the identification of structural abnormalities made possible by modern imaging techniques. The association between meningoencephaloceles and epileptic seizures is well reported in the literature. We report a patient with refractory right frontal lobe epilepsy caused by a right nasal meningoencephalocele who was rendered ...
متن کاملMicrodysgenesis in temporal lobe epilepsy. A quantitative and immunohistochemical study of white matter neurones.
Microdysgenesis is a microscopic cortical malformation considered to act as a substrate for seizures in some patients with generalized epilepsy. It is also recognized to involve the temporal lobe in a proportion of patients with intractable temporal lobe epilepsy, but the incidence of this abnormality, its relationship to mesial temporal lobe sclerosis and relevance to epileptogenesis remain un...
متن کاملFamilial temporal lobe epilepsy due to focal cortical dysplasia type IIIa
PURPOSE Focal cortical dysplasia (FCD) represents a common cause of refractory epilepsy. It is considered a sporadic disorder, but its occasional familial occurrence suggests the involvement of genetic mechanisms. METHODS Siblings with intractable epilepsy were referred for epilepsy surgery evaluation. Both patients were examined using video-EEG monitoring, MRI examination and PET imaging. Th...
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ورودعنوان ژورنال:
- Seizure
دوره 23 شماره
صفحات -
تاریخ انتشار 2014